Tobacco remains the leading preventable cause of death in the United States. Its effects are felt more heavily in certain populations that are intentionally targeted by the tobacco and vape industry. Beyond the unequal burden of death and disease in these communities, the industry causes irreversible harm to the environment, manipulates government systems, and avoids accountability through loopholes in regulation—making tobacco not only a public health issue, but one tied to deeper systemic problems. This training provides examples of how the tobacco industry abuses its power. It also introduces the UpRISE youth movement, which is designed to amplify the voices of young people targeted by tobacco companies and to identify and address the root causes of nicotine use.